Substances Generally Recognized As Safe

§ 582.1 — Substances that are generally recognized as safe.

(a) It is impracticable to list all substances that are generally recognized as safe for their intended use. However, by way of illustration, the Commissioner regards such common food ingredients as salt, pepper, sugar, vinegar, baking powder, and monosodium glutamate as safe for their intended use. The lists in subparts B through H of this part include additional substances that, when used for the purposes indicated, in accordance with good manufacturing or feeding practice, are regarded by the Commissioner as generally recognized as safe for such uses.

(b) For the purposes of this section, good manufacturing or feeding practice shall be defined to include the following restrictions:

(1) The quantity of a substance added to animal food does not exceed the amount reasonably required to accomplish its intended physical, nutritional, or other technical effect in food; and

(2) The quantity of a substance that becomes a component of animal food as a result of its use in the manufacturing, processing, or packaging of food, and which is not intended to accomplish any physical or other technical effect in the food itself, shall be reduced to the extent reasonably possible.

(3) The substance is of appropriate grade and is prepared and handled as a food ingredient. Upon request the Commissioner will offer an opinion, based on specifications and intended use, as to whether or not a particular grade or lot of the substance is of suitable purity for use in food and would generally be regarded as safe for the purpose intended, by experts qualified to evaluate its safety.

(c) The inclusion of substances in the list of nutrients does not constitute a finding on the part of the Department that the substance is useful as a supplement to the diet for animals.

(d) Substances that are generally recognized as safe for their intended use within the meaning of section 409 of the Act are listed in subparts B through H of this part. When the status of a substance has been reevaluated and affirmed as GRAS or deleted from subparts B through H of this part, an appropriate explanation will be noted, e.g., “affirmed as GRAS,” “food additive regulation,” “interim food additive regulation,” or “prohibited from use in food,” with a reference to the appropriate new regulation. Such notation will apply only to the specific use covered by the review, e.g., direct animal food use and/or indirect animal food use and/or animal feed use and will not affect its status for other uses not specified in the referenced regulation, pending a specific review of such other uses.

§ 582.10 — Spices and other natural seasonings and flavorings.

Spices and other natural seasonings and flavorings that are generally recognized as safe for their intended use, within the meaning of section 409 of the act, are as follows:

§ 582.20 — Essential oils, oleoresins (solvent-free), and natural extractives (including distillates).

Essential oils, oleoresins (solvent-free), and natural extractives (including distillates) that are generally recognized as safe for their intended use, within the meaning of section 409 of the act, are as follows:

§ 582.30 — Natural substances used in conjunction with spices and other natural seasonings and flavorings.

Natural substances used in conjunction with spices and other natural seasonings and flavorings that are generally recognized as safe for their intended use, within the meaning of section 409 of the act, are as follows:

§ 582.40 — Natural extractives (solvent-free) used in conjunction with spices, seasonings, and flavorings.

Natural extractives (solvent-free) used in conjunction with spices, seasonings, and flavorings that are generally recognized as safe for their intended use, within the meaning of section 409 of the act, are as follows:

§ 582.50 — Certain other spices, seasonings, essential oils, oleoresins, and natural extracts.

Certain other spices, seasonings, essential oils, oleoresins, and natural extracts that are generally recognized as safe for their intended use, within the meaning of section 409 of the act, are as follows:

§ 582.60 — Synthetic flavoring substances and adjuvants.

Synthetic flavoring substances and adjuvants that are generally recognized as safe for their intended use, within the meaning of section 409 of the act, are as follows:

§ 582.80 — Trace minerals added to animal feeds.

These substances added to animal feeds as nutritional dietary supplements are generally recognized as safe when added at levels consistent with good feeding practice. 1

§ 582.99 — Adjuvants for pesticide chemicals.

Adjuvants, identified and used in accordance with 40 CFR 180.910 and 180.920, which are added to pesticide use dilutions by a grower or applicator prior to application to the raw agricultural commodity, are exempt from the requirement of tolerances under section 409 of the act.

§ 582.1005 — Acetic acid.

(a) Product. Acetic acid.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1009 — Adipic acid.

(a) Product. Adipic acid.

(b) [Reserved]

(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used as a buffer and neutralizing agent in accordance with good manufacturing or feeding practice.

§ 582.1033 — Citric acid.

(a) Product. Citric acid.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1057 — Hydrochloric acid.

(a) Product. Hydrochloric acid.

(b) [Reserved]

(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used as a buffer and neutralizing agent in accordance with good manufacturing or feeding practice.

§ 582.1061 — Lactic acid.

(a) Product. Lactic acid.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1069 — Malic acid.

(a) Product. Malic acid.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1073 — Phosphoric acid.

(a) Product. Phosphoric acid.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1077 — Potassium acid tartrate.

(a) Product. Potassium acid tartrate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1087 — Sodium acid pyrophosphate.

(a) Product. Sodium acid pyrophosphate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1091 — Succinic acid.

(a) Product. Succinic acid.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1095 — Sulfuric acid.

(a) Product. Sulfuric acid.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1099 — Tartaric acid.

(a) Product. Tartaric acid.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1125 — Aluminum sulfate.

(a) Product. Aluminum sulfate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1127 — Aluminum ammonium sulfate.

(a) Product. Aluminum ammonium sulfate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1129 — Aluminum potassium sulfate.

(a) Product. Aluminum potassium sulfate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1131 — Aluminum sodium sulfate.

(a) Product. Aluminum sodium sulfate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1135 — Ammonium bicarbonate.

(a) Product. Ammonium bicarbonate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1137 — Ammonium carbonate.

(a) Product. Ammonium carbonate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1139 — Ammonium hydroxide.

(a) Product. Ammonium hydroxide.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1141 — Ammonium phosphate.

(a) Product. Ammonium phosphate (mono- and dibasic).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1143 — Ammonium sulfate.

(a) Product. Ammonium sulfate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1155 — Bentonite.

(a) Product. Bentonite.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1165 — Butane.

(a) Product. Butane.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1191 — Calcium carbonate.

(a) Product. Calcium carbonate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1193 — Calcium chloride.

(a) Product. Calcium chloride.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1195 — Calcium citrate.

(a) Product. Calcium citrate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1199 — Calcium gluconate.

(a) Product. Calcium gluconate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1205 — Calcium hydroxide.

(a) Product. Calcium hydroxide.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1207 — Calcium lactate.

(a) Product. Calcium lactate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1210 — Calcium oxide.

(a) Product. Calcium oxide.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1217 — Calcium phosphate.

(a) Product. Calcium phosphate (mono-, di-, and tribasic).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1235 — Caramel.

(a) Product. Caramel.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1240 — Carbon dioxide.

(a) Product. Carbon dioxide.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1275 — Dextrans.

(a) Product. Dextrans of average molecular weight below 100,000.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1320 — Glycerin.

(a) Product. Glycerin.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1324 — Glyceryl monostearate.

(a) Product. Glyceryl monostearate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1355 — Helium.

(a) Product. Helium.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1366 — Hydrogen peroxide.

(a) Product. Hydrogen peroxide.

(b) [Reserved]

(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used as a bleaching agent in accordance with good manufacturing or feeding practice.

§ 582.1400 — Lecithin.

(a) Product. Lecithin.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1425 — Magnesium carbonate.

(a) Product. Magnesium carbonate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1428 — Magnesium hydroxide.

(a) Product. Magnesium hydroxide.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1431 — Magnesium oxide.

(a) Product. Magnesium oxide.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1480 — Methylcellulose.

(a) Product. U.S.P. methylcellulose, except that the methoxy content shall not be less than 27.5 percent and not more than 31.5 percent on a dry-weight basis.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1500 — Monoammonium glutamate.

(a) Product. Monoammonium glutamate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1516 — Monopotassium glutamate.

(a) Product. Monopotassium glutamate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1540 — Nitrogen.

(a) Product. Nitrogen.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1585 — Papain.

(a) Product. Papain.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1613 — Potassium bicarbonate.

(a) Product. Potassium bicarbonate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1619 — Potassium carbonate.

(a) Product. Potassium carbonate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1625 — Potassium citrate.

(a) Product. Potassium citrate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1631 — Potassium hydroxide.

(a) Product. Potassium hydroxide.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1643 — Potassium sulfate.

(a) Product. Potassium sulfate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1655 — Propane.

(a) Product. Propane.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1666 — Propylene glycol.

(a) Product. Propylene glycol.

(b) Conditions of use. This substance is generally recognized as safe (except in cat food) when used in accordance with good manufacturing or feeding practice.

§ 582.1685 — Rennet.

(a) Product. Rennet (rennin).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1711 — Silica aerogel.

(a) Product. Silica aerogel as a finely powdered microcellular silica foam having a minimum silica content of 89.5 percent.

(b) [Reserved]

(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used as a component of antifoaming agents in accordance with good manufacturing or feeding practice.

§ 582.1721 — Sodium acetate.

(a) Product. Sodium acetate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1736 — Sodium bicarbonate.

(a) Product. Sodium bicarbonate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1742 — Sodium carbonate.

(a) Product. Sodium carbonate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1745 — Sodium carboxymethylcellulose.

(a) Product. Sodium carboxymethyl- cellulose is the sodium salt of carboxymethylcellulose not less than 99.5 percent on a dry-weight basis, with maximum substitution of 0.95 carboxymethyl groups per anhydroglucose unit, and with a minimum viscosity of 25 centipoises for 2 percent by weight aqueous solution at 25 °C.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1748 — Sodium caseinate.

(a) Product. Sodium caseinate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1751 — Sodium citrate.

(a) Product. Sodium citrate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1763 — Sodium hydroxide.

(a) Product. Sodium hydroxide.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1775 — Sodium pectinate.

(a) Product. Sodium pectinate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1778 — Sodium phosphate.

(a) Product. Sodium phosphate (mono-, di-, and tribasic).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1781 — Sodium aluminum phosphate.

(a) Product. Sodium aluminum phosphate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1792 — Sodium sesquicarbonate.

(a) Product. Sodium sesquicarbonate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1804 — Sodium potassium tartrate.

(a) Product. Sodium potassium tartrate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1810 — Sodium tripolyphosphate.

(a) Product. Sodium tripolyphosphate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1901 — Triacetin.

(a) Product. Triacetin (glyceryl triacetate).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1973 — Beeswax.

(a) Product. Beeswax (yellow wax).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1975 — Bleached beeswax.

(a) Product. Bleached beeswax (white wax).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.1978 — Carnauba wax.

(a) Product. Carnauba wax.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.2122 — Aluminum calcium silicate.

(a) Product. Aluminum calcium silicate.

(b) Tolerance. 2 percent.

(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used in table salt in accordance with good manufacturing or feeding practice.

§ 582.2227 — Calcium silicate.

(a) Product. Calcium silicate.

(b) Tolerance. 2 percent and 5 percent.

(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used at levels not exceeding 2 percent in table salt and 5 percent in baking powder in accordance with good manufacturing or feeding practice.

§ 582.2437 — Magnesium silicate.

(a) Product. Magnesium silicate.

(b) Tolerance. 2 percent.

(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used in table salt in accordance with good manufacturing or feeding practice.

§ 582.2727 — Sodium aluminosilicate.

(a) Product. Sodium aluminosilicate (sodium silicoaluminate).

(b) Tolerance. This substance is generally recognized as safe for use at a level not exceeding 2 percent in accordance with good manufacturing or feeding practice.

§ 582.2729 — Hydrated sodium calcium aluminosilicate.

(a) Product. Hydrated sodium calcium aluminosilicate (sodium calcium silicoaluminate).

(b) Tolerance. This substance is generally recognized as safe for use at a level not exceeding 2 percent in accordance with good manufacturing or feeding practice.

§ 582.2906 — Tricalcium silicate.

(a) Product. Tricalcium silicate.

(b) Tolerance. 2 percent.

(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used in table salt in accordance with good manufacturing or feeding practice.

§ 582.3013 — Ascorbic acid.

(a) Product. Ascorbic acid.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.3021 — Benzoic acid.

(a) Product. Benzoic acid.

(b) Tolerance. This substance is generally recognized as safe for use at a level not exceeding 0.1 percent in accordance with good manufacturing or feeding practice.

§ 582.3041 — Erythorbic acid.

(a) Product. Erythorbic acid.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.3081 — Propionic acid.

(a) Product. Propionic acid.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.3089 — Sorbic acid.

(a) Product. Sorbic acid.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.3109 — Thiodipropionic acid.

(a) Product. Thiodipropionic acid.

(b) Tolerance. This substance is generally recognized as safe for use in food when the total content of antioxidants is not over 0.02 percent of fat or oil content including essential (volatile) oil content of the food, provided the substance is used in accordance with good manufacturing or feeding practice.

§ 582.3149 — Ascorbyl palmitate.

(a) Product. Ascorbyl palmitate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.3169 — Butylated hydroxyanisole.

(a) Product. Butylated hydroxyanisole.

(b) Tolerance. This substance is generally recognized as safe for use in food when the total content of antioxidants is not over 0.02 percent of fat or oil content, including essential (volatile) oil content of food provided the substance is used in accordance with good manufacturing or feeding practice.

§ 582.3173 — Butylated hydroxytoluene.

(a) Product. Butylated hydroxytol- uene.

(b) Tolerance. This substance is generally recognized as safe for use in food when the total content of antioxidants is not over 0.02 percent of fat or oil content, including essential (volatile) oil content of food provided the substance is used in accordance with good manufacturing or feeding practice.

§ 582.3189 — Calcium ascorbate.

(a) Product. Calcium ascorbate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.3221 — Calcium propionate.

(a) Product. Calcium propionate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.3225 — Calcium sorbate.

(a) Product. Calcium sorbate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.3280 — Dilauryl thiodipropionate.

(a) Product. Dilauryl thiodipropionate.

(b) Tolerance. This substance is generally recognized as safe for use in food when the total content of antioxidants is not over 0.02 percent of fat or oil content, including essential (volatile) oil content of the food, provided the substance is used in accordance with good manufacturing or feeding practice.

§ 582.3336 — Gum guaiac.

(a) Product. Gum guaiac.

(b) Tolerance. 0.1 percent (equivalent antioxidant activity 0.01 percent).

(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used in edible fats or oils in accordance with good manufacturing or feeding practice.

§ 582.3490 — Methylparaben.

(a) Product. Methylparaben (methyl p-hydroxybenzoate).

(b) Tolerance. This substance is generally recognized as safe for use at a level not exceeding 0.1 percent in accordance with good manufacturing or feeding practice.

§ 582.3616 — Potassium bisulfite.

(a) Product. Potassium bisulfite.

(b) [Reserved]

(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice, except that it is not used in meats or in food recognized as source of vitamin B1.

§ 582.3637 — Potassium metabisulfite.

(a) Product. Potassium metabisulfite.

(b) [Reserved]

(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice, except that it is not used in meats or in food recognized as source of vitamin B1.

§ 582.3640 — Potassium sorbate.

(a) Product. Potassium sorbate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.3660 — Propyl gallate.

(a) Product. Propyl gallate.

(b) Tolerance. This substance is generally recognized as safe for use in food when the total content of antioxidants is not over 0.02 percent of fat or oil content, including essential (volatile) oil content of the food, provided the substance is used in accordance with good manufacturing or feeding practice.

§ 582.3670 — Propylparaben.

(a) Product. Propylparaben (propyl p-hydroxybenzoate).

(b) Tolerance. This substance is generally recognized as safe for use at a level not exceeding 0.1 percent in accordance with good manufacturing or feeding practice.

§ 582.3731 — Sodium ascorbate.

(a) Product. Sodium ascorbate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.3733 — Sodium benzoate.

(a) Product. Sodium benzoate.

(b) Tolerance. This substance is generally recognized as safe for use at a level not exceeding 0.1 percent in accordance with good manufacturing or feeding practice.

§ 582.3739 — Sodium bisulfite.

(a) Product. Sodium bisulfite.

(b) [Reserved]

(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice, except that it is not used in meats or in food recognized as source of vitamin B1.

§ 582.3766 — Sodium metabisulfite.

(a) Product. Sodium metabisulfite.

(b) [Reserved]

(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice, except that it is not used in meats or in food recognized as source of vitamin B1.

§ 582.3784 — Sodium propionate.

(a) Product. Sodium propionate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.3795 — Sodium sorbate.

(a) Product. Sodium sorbate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.3798 — Sodium sulfite.

(a) Product. Sodium sulfite.

(b) [Reserved]

(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice, except that it is not used in meats or in food recognized as source of vitamin B1.

§ 582.3845 — Stannous chloride.

(a) Product. Stannous chloride.

(b) Tolerance. This substance is generally recognized as safe for use at a level not exceeding 0.0015 percent calculated as tin in accordance with good manufacturing or feeding practice.

§ 582.3862 — Sulfur dioxide.

(a) Product. Sulfur dioxide.

(b) [Reserved]

(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice, except that it is not used in meats or in food recognized as source of vitamin B1.

§ 582.3890 — Tocopherols.

(a) Product. Tocopherols.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.4101 — Diacetyl tartaric acid esters of mono- and diglycerides of edible fats or oils, or edible fat-forming fatty acids.

(a) Product. Diacetyl tartaric acid esters of mono- and diglycerides of edible fats or oils, or edible fat-forming fatty acids.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.4505 — Mono- and diglycerides of edible fats or oils, or edible fat-forming acids.

(a) Product. Mono- and diglycerides of edible fats or oils, or edible fat-forming acids.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.4521 — Monosodium phosphate derivatives of mono- and diglycerides of edible fats or oils, or edible fat-forming fatty acids.

(a) Product. Monosodium phosphate derivatives of mono- and diglycerides of edible fats or oils, or edible fat-forming fatty acids.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.4666 — Propylene glycol.

(a) Product. Propylene glycol.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5013 — Ascorbic acid.

(a) Product. Ascorbic acid.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5017 — Aspartic acid.

(a) Product. Aspartic acid (L- and DL-forms).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5049 — Aminoacetic acid.

(a) Product. Glycine (aminoacetic acid).

(b) [Reserved]

(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used in animal feeds in accordance with good manufacturing or feeding practice.

§ 582.5065 — Linoleic acid.

(a) Product. Linoleic acid prepared from edible fats and oils and free from chick-edema factor.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5118 — Alanine.

(a) Product. Alanine (L- and DL-forms).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5145 — Arginine.

(a) Product. Arginine (L- and DL-forms).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5159 — Biotin.

(a) Product. Biotin.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5191 — Calcium carbonate.

(a) Product. Calcium carbonate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5195 — Calcium citrate.

(a) Product. Calcium citrate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5201 — Calcium glycerophosphate.

(a) Product. Calcium glycerophosphate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5210 — Calcium oxide.

(a) Product. Calcium oxide.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5212 — Calcium pantothenate.

(a) Product. Calcium pantothenate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5217 — Calcium phosphate.

(a) Product. Calcium phosphate (mono-, di-, and tribasic).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5223 — Calcium pyrophosphate.

(a) Product. Calcium pyrophosphate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5230 — Calcium sulfate.

(a) Product. Calcium sulfate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5245 — Carotene.

(a) Product. Carotene.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5250 — Choline bitartrate.

(a) Product. Choline bitartrate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5252 — Choline chloride.

(a) Product. Choline chloride.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5260 — Copper gluconate.

(a) Product. Copper gluconate.

(b) Tolerance. This substance is generally recognized as safe for use at a level not exceeding 0.005 percent in accordance with good manufacturing or feeding practice.

§ 582.5271 — Cysteine.

(a) Product. Cysteine (L-forms).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5273 — Cystine.

(a) Product. Cystine (L- and DL-forms).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5301 — Ferric phosphate.

(a) Product. Ferric phosphate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5304 — Ferric pyrophosphate.

(a) Product. Ferric pyrophosphate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5306 — Ferric sodium pyrophosphate.

(a) Product. Ferric sodium pyrophosphate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5308 — Ferrous gluconate.

(a) Product. Ferrous gluconate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5311 — Ferrous lactate.

(a) Product. Ferrous lactate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5315 — Ferrous sulfate.

(a) Product. Ferrous sulfate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5361 — Histidine.

(a) Product. Histidine (L- and DL-forms).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5370 — Inositol.

(a) Product. Inositol.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5375 — Iron reduced.

(a) Product. Iron reduced.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5381 — Isoleucine.

(a) Product. Isoleucine (L- and DL-forms).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5406 — Leucine.

(a) Product. Leucine (L- and DL-forms).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5411 — Lysine.

(a) Product. Lysine (L- and DL-forms).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5431 — Magnesium oxide.

(a) Product. Magnesium oxide.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5434 — Magnesium phosphate.

(a) Product. Magnesium phosphate (di- and tribasic).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5443 — Magnesium sulfate.

(a) Product. Magnesium sulfate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5446 — Manganese chloride.

(a) Product. Manganese chloride.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5449 — Manganese citrate.

(a) Product. Manganese citrate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5452 — Manganese gluconate.

(a) Product. Manganese gluconate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5455 — Manganese glycerophosphate.

(a) Product. Manganese glycerophosphate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5458 — Manganese hypophosphite.

(a) Product. Manganese hypophosphite.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5461 — Manganese sulfate.

(a) Product. Manganese sulfate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5464 — Manganous oxide.

(a) Product. Manganous oxide.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5470 — Mannitol.

(a) Product. Mannitol.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5475 — Methionine.

(a) Product. Methionine.

(b) [Reserved]

(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used in animal feeds in accordance with good manufacturing or feeding practice.

§ 582.5477 — Methionine hydroxy analog and its calcium salts.

(a) Product. Methionine hydroxy analog and its calcium salts.

(b) [Reserved]

(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used in animal feeds in accordance with good manufacturing or feeding practice.

§ 582.5530 — Niacin.

(a) Product. Niacin.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5535 — Niacinamide.

(a) Product. Niacinamide.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5580 — D-Pantothenyl alcohol.

(a) Product. D-Pantothenyl alcohol.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5590 — Phenylalanine.

(a) Product. Phenylalanine (L- and DL-forms).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5622 — Potassium chloride.

(a) Product. Potassium chloride.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5628 — Potassium glycerophosphate.

(a) Product. Potassium glycerophosphate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5634 — Potassium iodide.

(a) Product. Potassium iodide.

(b) Tolerance. 0.01 percent.

(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used in table salt as a source of dietary iodine in accordance with good manufacturing or feeding practice.

§ 582.5650 — Proline.

(a) Product. Proline (L- and DL-forms).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5676 — Pyridoxine hydrochloride.

(a) Product. Pyridoxine hydrochloride.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5695 — Riboflavin.

(a) Product. Riboflavin.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5697 — Riboflavin-5-phosphate.

(a) Product. Riboflavin-5-phosphate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5701 — Serine.

(a) Product. Serine (L- and DL-forms).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5772 — Sodium pantothenate.

(a) Product. Sodium pantothenate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5778 — Sodium phosphate.

(a) Product. Sodium phosphate (mono-, di-, and tribasic).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5835 — Sorbitol.

(a) Product. Sorbitol.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5875 — Thiamine hydrochloride.

(a) Product. Thiamine hydrochloride.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5878 — Thiamine mononitrate.

(a) Product. Thiamine mononitrate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5881 — Threonine.

(a) Product. Threonine (L- and DL-forms).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5890 — Tocopherols.

(a) Product. Tocopherols.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5892

(a) Product. a-Tocopherol acetate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5915 — Tryptophane.

(a) Product. Tryptophane (L- and DL-forms).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5920 — Tyrosine.

(a) Product. Tyrosine (L- and DL-forms).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5925 — Valine.

(a) Product. Valine (L- and DL-forms).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5930 — Vitamin A.

(a) Product. Vitamin A.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5933 — Vitamin A acetate.

(a) Product. Vitamin A acetate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5936 — Vitamin A palmitate.

(a) Product. Vitamin A palmitate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5945 — Vitamin B

(a) Product. Vitamin B12.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5950 — Vitamin D

(a) Product. Vitamin D2.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5953 — Vitamin D

(a) Product. Vitamin D3.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5985 — Zinc chloride.

(a) Product. Zinc chloride.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5988 — Zinc gluconate.

(a) Product. Zinc gluconate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5991 — Zinc oxide.

(a) Product. Zinc oxide.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5994 — Zinc stearate.

(a) Product. Zinc stearate prepared from stearic acid free from chick-edema factor.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.5997 — Zinc sulfate.

(a) Product. Zinc sulfate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.6033 — Citric acid.

(a) Product. Citric acid.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.6085 — Sodium acid phosphate.

(a) Product. Sodium acid phosphate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.6099 — Tartaric acid.

(a) Product. Tartaric acid.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.6185 — Calcium acetate.

(a) Product. Calcium acetate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.6193 — Calcium chloride.

(a) Product. Calcium chloride.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.6195 — Calcium citrate.

(a) Product. Calcium citrate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.6197 — Calcium diacetate.

(a) Product. Calcium diacetate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.6199 — Calcium gluconate.

(a) Product. Calcium gluconate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.6203 — Calcium hexametaphosphate.

(a) Product. Calcium hexametaphosphate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.6215 — Monobasic calcium phosphate.

(a) Product. Monobasic calcium phosphate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.6219 — Calcium phytate.

(a) Product. Calcium phytate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.6285 — Dipotassium phosphate.

(a) Product. Dipotassium phosphate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.6290 — Disodium phosphate.

(a) Product. Disodium phosphate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.6386 — Isopropyl citrate.

(a) Product. Isopropyl citrate.

(b) Tolerance. This substance is generally recognized as safe for use at a level not exceeding 0.02 percent in accordance with good manufacturing or feeding practice.

§ 582.6511 — Monoisopropyl citrate.

(a) Product. Monoisopropyl citrate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.6625 — Potassium citrate.

(a) Product. Potassium citrate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.6751 — Sodium citrate.

(a) Product. Sodium citrate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.6754 — Sodium diacetate.

(a) Product. Sodium diacetate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.6757 — Sodium gluconate.

(a) Product. Sodium gluconate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.6760 — Sodium hexametaphosphate.

(a) Product. Sodium hexametaphosphate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.6769 — Sodium metaphosphate.

(a) Product. Sodium metaphosphate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.6778 — Sodium phosphate.

(a) Product. Sodium phosphate (mono-, di-, and tribasic).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.6787 — Sodium pyrophosphate.

(a) Product. Sodium pyrophosphate.

(b) Condition of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.6789 — Tetra sodium pyrophosphate.

(a) Product. Tetra sodium pyrophosphate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.6801 — Sodium tartrate.

(a) Product. Sodium tartrate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.6804 — Sodium potassium tartrate.

(a) Product. Sodium potassium tartrate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.6807 — Sodium thiosulfate.

(a) Product. Sodium thiosulfate.

(b) Tolerance. 0.1 percent.

(c) Limitations, restrictions, or explanation. This substance is generally recognized as safe when used in salt in accordance with good manufacturing or feeding practice.

§ 582.6810 — Sodium tripolyphosphate.

(a) Product. Sodium tripolyphosphate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.6851 — Stearyl citrate.

(a) Product. Stearyl citrate.

(b) Tolerance. This substance is generally recognized as safe for use at a level not exceeding 0.15 percent in accordance with good manufacturing or feeding practice.

§ 582.7115 — Agar-agar.

(a) Product. Agar-agar.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.7133 — Ammonium alginate.

(a) Product. Ammonium alginate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.7187 — Calcium alginate.

(a) Product. Calcium alginate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.7255 — Chondrus extract.

(a) Product. Chondrus extract (carrageenin).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.7330 — Gum arabic.

(a) Product. Acacia (gum arabic).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.7333 — Gum ghatti.

(a) Product. Gum ghatti.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.7339 — Guar gum.

(a) Product. Guar gum.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.7343 — Locust bean gum.

(a) Product. Locust (carob) bean gum.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.7349 — Sterculia gum.

(a) Product. Sterculia gum (karaya gum).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.7351 — Gum tragacanth.

(a) Product. Tragacanth (gum tragacanth).

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.7610 — Potassium alginate.

(a) Product. Potassium alginate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.

§ 582.7724 — Sodium alginate.

(a) Product. Sodium alginate.

(b) Conditions of use. This substance is generally recognized as safe when used in accordance with good manufacturing or feeding practice.